Polarized light microscopes are used to observe samples. 

At this time there are no scheduled dates for this course.

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Course Details

Course Outline
  • History and uses of thermal microscopy
  • Instrumentation and sample preparation
  • Calibration and performance verification
  • Observations on heating and cooling
  • Polymorphism and racemic mixtures
  • Liquid crystals
  • Fusion techniques
  • Freeze dry microscopy
  • Summary and recommendations for further study
What You Will Learn

Upon satisfactory completion of this course students have:

  • Knowledge of applications of TM in pharmaceutical development
  • Knowledge of required instrumentation
  • Practice in instrument setup, thermal stage calibration, and performance validation
  • Practice in using TM for solid-state form discovery, for form understanding, for determination of stable form at ambient conditions, and for determination of polymorph transition temperature
  • Practice is use of fusion techniques for chemical identification and for determination of polymorph transition temperature
  • Practice in use of TM in the study of liquid crystals
  • Knowledge of the use of TM in the study of racemic mixtures
  • Knowledge of freeze dry microscopy and the determination of cake collapse temperature
Who Should Enroll

This course is intended for pharmaceutical scientists who need a good understanding of thermal microscopy and how it is used to help develop proficiency with solid-state drug properties.

Job titles for students taking this course include instrument operators, lab facility managers, materials scientists, technicians, and advanced undergraduates or graduate students.

Suggested Prerequisites
  • Basic knowledge of solid-state chemistry as applied to pharmaceuticals
  • Facility in use of polarized light microscopy for drug imaging
  • Basic computer skills
Student Learning Resources

All necessary materials and instruments will be provided to the student for classroom use.

Satisfactory Completion Requirements

Students are expected to successfully complete a variety of tasks in the form of hands-on exercises, laboratory exercises, identifications of unknowns, and quizzes. Students are notified at the end of the course whether or not they have successfully completed the requirements of the course based on:

  • 100% Attendance
  • Class participation
  • Completion of all course material
  • Completed and signed student evaluation form

Upon successfully meeting these requirements, a student is awarded a certificate of completion and CEU credits, if available. Those who have not successfully passed the course requirements do not receive a certificate or CEU credits.

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